The body contain many unique physiologic systems whose sole purpose is to maintain an internal balance called homeostasis. We know the pancreas releases insulin to balance sugar levels between the bloodstream and cells. The thyroid gland releases thyroid hormone, which regulates vital bodily processes linked to metabolism, body temperature and much more. Simply put, our bodies are working constantly to stay balanced in response to our external environment.
In the quest to know the way THC causes its well known intoxicating effects, scientists found that we have yet another regulatory physiologic system, known as the endocannabinoid system (ECS), whose role is to maintain homeostasis of the messages sent between our cells. Further research has revealed that sickness, inflammation, and injury will trigger the ECS to consider action, attempting to reset our internal environment to homeostasis. This method continues to be referred to as being protective and required for life. What happens if we might target this system to avoid illness and keep better health?
Endocannabinoids, also known as our “inner cannabis,” are synthesized at will from healthy causes of dietary fat. Cannabinoid receptors sit on the membranes of cells in some elements of your brain and the body, namely areas inside the brain that control pain, memory, emotion, motor control, nausea, and appetite, and also the gut, immunity mechanism, and peripheral neurological system. Should there be a trigger that triggers an imbalance, such as an accident or illness, endocannabinoids are released, acting as “keys” that bind to the receptors, which act as “locks” on our cells. After the receptor is activated, a chemical reaction occurs within the cell, telling the cell to change its message.
ECS functioning is dependent upon many factors, including genetics, age, stress levels, diet, and overall degree of health. There can be variants in the genes that code for the ECS which can cause propensities for certain conditions, including ADHD and PTSD. Additionally, chronic illness, chronic stress or chronic sleep deprivation may lead to depletion in the endocannabinoids. These disruptions inside the normal functioning in the ECS hinder its ability to regulate cellular imbalances and achieve homeostasis.
In 2004, Ethan Russo, a neurologist and research scientist, published Clinical endocannabinoids Deficiency (CECD): Can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? in the journal Neuroendocrinology Letters. Russo theorized that particular people who have the listed conditions responded to cannabis-based treatments because they had endocannabinoid deficiencies that allowed the problem to manifest to start with.
Subsequent research has demonstrated that endocannabinoid deficiency plays a role in autoimmune diseases, epilepsy, complex regional pain syndrome, heart problems, depression, anxiety, schizophrenia, multiple sclerosis, nausea, Huntington’s disease, Parkinson’s disease, menstrual symptoms, failure to thrive in newborns, along with other difficult-to-treat conditions.
The cannabis plant produces over 100 phytocannabinoids, including tetrahydrocannabinol (THC) and cannabidiol (CBD). These compounds mimic the endocannabinoids by interacting with the ECS and restoring homeostasis. Rather than wait until illness is present, there are many ways to take good care of your ECS, which will allow it to function properly, avoid deficiencies and maintain homeostasis.
It’s common knowledge that the healthy, balanced weight loss program is required for emotional and physical well-being. The body depend on our diet to produce the correct quantity of endocannabinoids to operate at optimal capacity. Cannabinoids are synthesized from your essential fatty acids inside our diets and need a specific balance of omega-6 and omega-3 to become manufactured in the best quantities.
For max bioavailability, the optimal ratio of omega-6 to omega-3 essential fatty acids from food is between 5:1 and 1:1, the lower the higher for all those with chronic illness. Western diets routinely include ratios of 20:1, mainly as a result of overconsumption of omega-6 fatty acids which result from vegetable oils in numerous packaged foods. Western diets with higher ratios of omega-6 to omega-3 essential fatty acids results in a reduction of endocannabinoids, leading to the lack of ability to maintain homeostasis.
Another factor that promotes well-being from the ECS is cardio exercise. Animal studies report that voluntary wheel running increases cannabinoid receptors inside the brain and boosts the sensitivity in the receptors to endocannabinoids. Human research indicates that exercise such as running, biking and hiking enhance endocannabinoid levels within the bloodstream. Actually, endocannabinoids are probably responsible for the phenomenon described as the “runner’s high.”
Probiotics may also benefit the ECS. Lactobacillus acidophilus, a probiotic bacteria found in fermented foods including yogurt and sauerkraut, was shown to induce the expression of cannabinoid receptors inside the gut, promoting intestinal homeostasis.
Both acupuncture and osteopathic manipulation enhance the ECS. Yoga and meditation elicit the “relaxation response,” a physiological wjeflf phenomenon whereby anybody can consciously take part in behavior that promotes physical and mental wellness; although no research has been completed to date, most experts suspect these stress management modalities improve the ECS thereby promoting homeostasis.
Lastly, have you thought about the ability of cannabis to avoid illness? Plant cannabinoids are very well-considered to be very safe and also to have anti-inflammatory, antioxidant and neuroprotective properties. In cases of endocannabinoid deficiency, cannabis use could be the correcting compound, eliminating the signs and symptoms of the disorder. Regular cannabis use can decrease chronic inflammation and buildup of toxins, each of which are considered to be the basis causes of many conditions, including autoimmune and neurodegenerative disorders.